1,2,3,4-Tetrahydroisoquinoline-2-sulfonamide
نویسندگان
چکیده
The title compound, C(9)H(12)N(2)O(2)S, is a useful precursor of a variety of modified sulfonamide mol-ecules. Due to the importance of these mol-ecules in biological systems (antibacterials, antidepressants and many other applications), there is a growing inter-est in the discovery of new biologically active compounds. In the title compound, the mol-ecules are linked by N-H⋯O inter-molecular hydrogen bonds involving the sulfonamide function to form an infinite two-dimensional network parallel to the (001) plane.
منابع مشابه
(S)-Benzyl 3-phenylcarbamoyl-1,2,3,4-tetrahydroisoquinoline-2-carboxylate
There are two independent mol-ecules in the asymmetric unit of the title compound, C(24)H(22)N(2)O(3). The heterocyclic ring assumes a twisted boat conformation and N-H⋯O inter-actions help to construct the three-dimensional network within the crystal packing.
متن کامل(1S,3S)-Methyl 2-benzyl-6,7-dimethoxy-1-phenyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylate
In the title compound, C(26)H(27)NO(4), the heterocyclic ring assumes a half-chair conformation and inter-molecular C-H⋯O inter-actions help to construct the three-dimensional network within the crystal packing.
متن کامل(1,2,3,4-Tetrahydroisoquinoline-2-carbodithioato-κ2 S,S′)(thiocyanato-κN)(triphenylphosphane)nickel(II)
The Ni(II) atom in the mononuclear title compound, [Ni(C(10)H(10)NS(2))(NCS)(C(18)H(15)P)], exists within a S(2)PN donor set that defines a distorted square-planar geometry. A significant asymmetry in the Ni-S bond lengths support the less effective trans effect of SCN(-) over PPh(3).
متن کامل2-(2-Iodophenyl)-1,2,3,4-tetrahydroisoquinoline-1-carbonitrile
In the title compound, C(16)H(13)IN(2), the two benzene rings make a dihedral angle of 67.26 (5)°. The six-membered heterocycle of the tetra-hydro-isoquinoline unit adopts a half-chair conformation. In the crystal, adjacent mol-ecules are linked by pairs of weak inter-molecular C-H⋯N hydrogen bonds, forming inversion dimers. An intra-molecular C-H⋯I close contact is also observed.
متن کامل(1R,3S)-Methyl 2-benzyl-6,7-dimethoxy-1-phenyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylate
In the title compound, C(26)H(27)NO(4), a precursor to novel chiral catalysts, the N-containing six-membered ring assumes a half-boat conformation. Various C-H⋯π interactions and intermolecular short contacts (C⋯H = 2.81-2.90 Å) link the mol-ecules together in the crystal structure.
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